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  • Title: [Superior mesenteric and portal vein thrombosis in a polycythemia vera patient with JAK2 mutation].
    Author: Araki N, Takimoto R, Chiba H, Araki H, Sato T, Iyama S, Hirakawa M, Ono K, Kawano Y, Takada K, Miyanishi K, Kobune M, Matsunaga T, Kato J, Nakamura T, Niitsu Y.
    Journal: Rinsho Ketsueki; 2007 Jul; 48(7):554-8. PubMed ID: 17695304.
    Abstract:
    A 47-year-old woman was admitted to our hospital in December 1994 with polycythemia. The patient's red blood cell volume was 33 ml/kg and bone marrow cytology was able to rule out other myeloproliferative diseases such as chronic myelogenous leukemia, essential thrombocytosis and myelofibrosis. The patient was diagnosed as having polycythemia vera. She had undergone only phlebotomy until 1999 when the thrombocytosis appeared, subsequent to which she was treated with oral hydroxyurea. However, in March 2006, she developed upper abdominal pain and was admitted to our hospital on March 14th, 2006. Computed tomography scan revealed thromboses in the portal and superior mesenteric veins. Anticoagulation therapy delivered intravenously via the superior mesenteric vein dramatically improved her symptoms and liver function. She is currently on anticoagulation therapy in our outpatient clinic.
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