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  • Title: Safety and efficiency of recombinant activated factor VII in postcardiotomy massive hemorrhage.
    Author: Lamarche Y, Demers P, Poirier NC, Robitaille D, Cartier R.
    Journal: Can J Cardiol; 2007 Aug; 23(10):809-13. PubMed ID: 17703260.
    Abstract:
    Postoperative massive hemorrhage is a difficult clinical situation after cardiac surgery. Recombinant activated factor VII (rf-VIIa) can be a useful adjunct to surgical hemostasis and blood product transfusion. Four cases of massive hemorrhage treated with rf-VIIa after complex cardiac surgery are reported. A review of the literature and possible guidelines for the use of rf-VIIa in cardiac surgery are provided. L’hémorragie massive postopératoire est une situation clinique difficile après une chirurgie cardiaque. Le facteur VII activé recombinant (rf-VIIa) peut être un ajout utile à l’hémostase chirurgicale et à la transfusion de produit sanguin. On rend compte de quatre cas d’hémorragie massive traités par rf-VIIa après une chirurgie cardiaque complexe. On fournit une analyse des publications scientifiques et des lignes directrices possibles sur l’utilisation du rf-VIIa en cas de chirurgie cardiaque.
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