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  • Title: Occlusion of iatrogenic pseudoaneurysms with percutaneous ultrasound guided thrombin injection.
    Author: Freund G, Dürschmied D, Zhou Q, Richter S, Macharzina R, Haas R, Becherer A, Bode C, Hehrlein C.
    Journal: Vasa; 2007 May; 36(2):96-9. PubMed ID: 17708100.
    Abstract:
    BACKGROUND: Pseudoaneurysm is a common complication of cardiac catheterization and coronary intervention with an incidence of 2% even in experienced centers. PATIENTS AND METHODS: In a feasibility study conducted between December 2004 and February 2006 we enrolled 76 patients consecutively to receive local thrombin injection (mean 329 IU; range 100-800 IU) into the aneurysma sac. RESULTS: Ultrasound guided thrombotic occlusion of pseudoaneurysms was successful after one injection in 83% of the patients, 17% of the patients required more than one injection. The overall success rate of the procedure was 98,9%. No peripheral embolisation of thrombin was noted during any injection and we registered no other complication that needed any further intervention. CONCLUSIONS: We conclude that ultrasound guided occlusion of pseudoaneurysms using thrombin injection with a success rate of the procedure of 98,9% is feasible and safe.
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