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  • Title: Acute ataxia, Graves' disease, and stiff person syndrome.
    Author: Chia SY, Chua R, Lo YL, Wong MC, Chan LL, Tan EK.
    Journal: Mov Disord; 2007 Oct 15; 22(13):1969-71. PubMed ID: 17712846.
    Abstract:
    Stiff person syndrome (SPS) has been associated with autoimmune diseases, such as Type 1 diabetes mellitus and autoimmune thyroid disease (Hashimoto's thyroiditis), among others. The association of SPS with hyperthyroidism is extremely rare. We describe a patient with uncontrolled Graves' disease and undiagnosed SPS, who presented initially with acute ataxia simulating a cerebrovascular accident. Initiation of immunosuppressive therapy dramatically improved the patient's Graves' disease within 2 weeks but the neurological symptoms were not alleviated after a follow-up period of 3 years.
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