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  • Title: [Explore of plateau period of amino acid metabolism kinetics].
    Author: Ji Y, Piao J, Gou L, Tian Y.
    Journal: Wei Sheng Yan Jiu; 2007 May; 36(3):352-4. PubMed ID: 17712960.
    Abstract:
    OBJECTIVE: To explore the plateau period of the enrichment of stable isotope for amino acid metabolism kinetics using the method of stable isotope tracer. METHODS: Selecting 5 healthy adults as subject, all of them were given 13C labeled leucine for 3 hours by their cutaneous veins on day 6 after 5 days adaption period. The respired air was collected during the course of infusion and 1 hour after infusion to determine the enrichment of 13C. RESULTS: The 13C enrichment in the respired air was at a higher level in 1 hour before infusion end and it will decrease immediately after the infusion end. CONCLUSION: It was suggested that one hour before infusion end is the optimal time for sampling in the study of metabolism kinetics of amino acid.
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