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  • Title: Rhodococcus equi lung infection in an allogeneic hematopoietic stem cell transplant recipient.
    Author: Cronin SM, Abidi MH, Shearer CJ, Chandrasekar PH, Ibrahim RB.
    Journal: Transpl Infect Dis; 2008 Feb; 10(1):48-51. PubMed ID: 17714438.
    Abstract:
    In this report, we describe a case of Rhodococcus equi lung infection diagnosed in an allogeneic hematopoietic stem cell transplant with oral graft-versus-host disease 3 months after stem cell infusion. The lung lesion persisted despite an approximate 3 months of vancomycin therapy, but then responded favorably to a combination of intravenous ertapenem at 1 g daily and oral rifampin at 600 mg daily for 1 month. An overview of Rhodococcus infection in transplant recipients is presented. This case and the discussed literature suggest that combination antibiotic therapy is warranted in patients with decreased humoral and cellular immunity.
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