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  • Title: Flexural allergic contact dermatitis to benzalkonium chloride in antiseptic bath oil.
    Author: Hann S, Hughes TM, Stone NM.
    Journal: Br J Dermatol; 2007 Oct; 157(4):795-8. PubMed ID: 17714561.
    Abstract:
    Benzalkonium chloride (BAK) is an acknowledged irritant but has also been identified as a cause of allergic contact dermatitis. The antiseptic bath emollient Oilatum Plus (Stiefel, High Wycombe, U.K.) contains a relatively high concentration of 6% BAK. We describe six patients who presented with flexural eczema, particularly involving the anogenital area, who had a history of using Oilatum Plus. Patch testing showed all six to have a type 4 allergy to BAK as well as other allergens. Avoidance of Oilatum Plus led to a resolution of the flexural eczema in each case.
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