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  • Title: Peripapillary intrachoroidal cavitation in high myopia: reappraisal.
    Author: Wei YH, Yang CM, Chen MS, Shih YF, Ho TC.
    Journal: Eye (Lond); 2009 Jan; 23(1):141-4. PubMed ID: 17721499.
    Abstract:
    PURPOSE: To evaluate optical coherence tomography (OCT) and clinical findings of a peripapillary lesion in high myopia recently named peripapillary detachment in pathologic myopia (PDPM) or intrachoroidal cavitation. METHODS: Observational case report by chart review, analysis of colour fundus photography, fluorescein angiography, and OCT in 16 eyes of 12 patients with myopic degeneration and the presence of a slightly elevated, patchy peripapillary, yellow-orange lesion on the fundus. RESULTS: Patients were mean age 53.1+/-10.7 years, with a spherical-equivalent refractive error of -10.99+/-3.33 D and mean axial length of 27.34+/-1.44 mm. The mean best-corrected visual acuity was log MAR 0.3+/-0.2 (between 20/100 and 20/20). Six eyes also showed myopic maculopathy. In 13 eyes, OCT showed an intrachoroidal hyporeflective space located below the normal plane of the retinal pigment epithelium. Six of these 13 eyes were found to have apparent communication between the intrachoroidal cavity and the vitreous space at the junction of the lesion and the myopic conus. In three eyes, OCT revealed intrachoroidal splitting. The fluorescein angiogram showed early hypofluorescence, without pooling or staining in late phase. CONCLUSIONS: The yellow-orange elevated patchy lesions adjacent to the peripapillary conus in high myopic eyes may represent either intrachoroidal cavitation or choroidal schisis, which may be different stages of one disease spectrum. Vitreous fluid may be the source of the disruption of choroid and fluid accumulation.
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