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  • Title: [Pathomorphological changes in the lung in tuberculosis patients died from HIV infection at the stage of AIDS].
    Author: Parkhomenko IuG, Erokhin VV, Ziuzia IuR, Lepekha LN, Tishkevich OA.
    Journal: Arkh Patol; 2007; 69(3):26-8. PubMed ID: 17722591.
    Abstract:
    The authors revealed the typical morphological changes of lung tuberculous lesion in HIV infection at the stage of AIDS: these included alterative changes without typical tuberculosis granulomas; a well-defined exsudative inflammatory component with a predominance of leukocytic infiltration and a drastically decrease of and, occasionally, a complete disappearance of macrophages and lymphocytes; formation of pyonecrotic foci; the focal monomorphic pattern illustrating the loss of the signs of process indulation. These signs suggest the specific features of immunity and the course of specific inflammation as immediate hypersensitivity with the acutest progression of tuberculosis.
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