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  • Title: Troponin I levels in patients with preeclampsia.
    Author: Joyal D, Leya F, Koh M, Besinger R, Ramana R, Kahn S, Jeske W, Lewis B, Steen L, Mestril R, Arab D.
    Journal: Am J Med; 2007 Sep; 120(9):819.e13-4. PubMed ID: 17765054.
    Abstract:
    INTRODUCTION: Preeclampsia involves a diffuse inflammatory state and elevated levels of troponins in patients with preeclampsia have been anecdotally reported. It is, however, unknown whether it is attributable to the preeclampsia. OBJECTIVE: We sought to determine the troponin I levels at the time of delivery in pregnant women with and without preeclampsia. METHODS: Plasma samples were obtained at the time of delivery and serum troponin I was measured by ELISA method. RESULTS: Thirty-nine women were included (20 with preeclampsia and 19 without). Mean troponin I level was 0.008 ng/mL in patients with preeclampsia and 0.01 ng/mL in controls (P =.59). The highest troponin I level was 0.04 ng/mL for both patients with and without preeclampsia. CONCLUSIONS: Preeclampsia was not associated with a rise in troponin I levels in our study. Patients with preeclampsia and elevated troponin levels should have further cardiac investigations.
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