These tools will no longer be maintained as of December 31, 2024. Archived website can be found here. PubMed4Hh GitHub repository can be found here. Contact NLM Customer Service if you have questions.


Pubmed for Handhelds

PUBMED FOR HANDHELDS

Search MEDLINE/PubMed

  • Title: CRP gene is involved in the regulation of human longevity: a follow-up study in Finnish nonagenarians.
    Author: Hurme M, Kivimäki M, Pertovaara M, Lehtimäki T, Karhunen PJ, Jylhä M, Hervonen A, Eklund C.
    Journal: Mech Ageing Dev; 2007 Oct; 128(10):574-6. PubMed ID: 17765290.
    Abstract:
    Chronic low-grade inflammation is involved in the pathogenesis of many disease conditions in humans and it is frequently quantified by measuring the blood concentration of C-reactive protein (CRP). Here we show that the CRP concentration in old people (nonagenarians) is, at least partially, genetically determined, and that the high producer genotype is associated with a shorter life expectancy during follow-up. Thus, the data imply that the CRP gene may be a longevity gene in humans.
    [Abstract] [Full Text] [Related] [New Search]