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  • Title: [Plasma amitriptyline level and its therapeutic effectiveness in patients with affective disorders].
    Author: Jakitowicz J.
    Journal: Psychiatr Pol; 1991; 25(1):13-20. PubMed ID: 1780369.
    Abstract:
    57 patients treated with amitriptyline because of depressive syndrome in the course of affective disorder were studied. The drug level in plasma was measured weakly using a gas chromatograph. A non-linear correlation between the amitriptyline level in plasma and the clinical effect of the treatment was substantiated. The range of therapeutic effectiveness was determined between 68.0 and 185.0 ng/ml.
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