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  • Title: [Digestive manifestations of common variable immunodeficiency].
    Author: Estrada Pérez V, Pérez de la Serna J, García Paredes J, Cortés León M, Gutiérrez Marcos FM, Estrada Sáiz RV.
    Journal: Rev Clin Esp; 1991 Feb; 188(3):142-6. PubMed ID: 1780514.
    Abstract:
    We present 4 cases of common variable immunodeficiency with main digestive clinical manifestations. In all four cases chronic diarrhea with intestinal malabsorption predominated, as well as the presence lymphoid nodular hyperplasia; in one case Giardia infestation could be identified; one patient also presented chronic pancreatitis, or recurrent aphthous stomatitis and active chronic hepatitis; sideroblastic anemia could be observed in another patient. All patients had favorable evolution during follow-up which lasted at least 14 months in substitutive treatment with immunoglobulins. One of our patients presented an elevated number of suppressor T lymphocytes, with inversion of the T helper/T suppressor ratio which improved with cimetidine treatment.
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