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  • Title: [Femoral osteosarcoma revealing onset of unifocal Paget's disease. Favourable course with 7-year follow-up].
    Author: Morlock G, Cadène C, Feru M, Durand J.
    Journal: Rev Rhum Mal Osteoartic; 1991 Nov 30; 58(11):813-7. PubMed ID: 1780659.
    Abstract:
    Sarcomatous degeneration is the most serious complication of Paget's disease, and few cases survive beyond 5 years. The authors report a new case, which occurred in a 62-year-old woman, in which calcifying periarthritis of the hip revealed the presence of a sarcoma developed in a context of a single bone case of Paget's disease affecting the upper extremity of the femur. Diagnosis was histological. The prognostic factors of Paget-related sarcomas are reviewed. The most important are the early timing of diagnosis and a site permitting radical surgical exeresis.
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