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  • Title: [Characteristics of lipid-hormone relations in the families of probands with early development of myocardial infarction].
    Author: Nikolaeva AA, Oteva EA, Shterental' ISh, Merzhievskaia VM, Maslennikov AB, Aksenovich TI.
    Journal: Sov Med; 1991; (12):6-10. PubMed ID: 1780786.
    Abstract:
    163 subjects from families whose probands developed myocardial infarction under the age of 50 were examined for plasma levels of total cholesterol, HDLP cholesterol, triglycerides, T3, T4, immunoreactive insulin (IRI) and cortisol. Four family groups were selected: probands (58), wives (41), sons (33), daughters (31). Lipid composition was investigated by standard techniques on Technicon AAP, a hormonal spectrum--by RIA using Soviet kits. It was established that alpha-cholesterolemia in the families was a common finding. Probands and their families combine reduced plasma T3 levels with high incidence of atherogenic dyslipoproteinemia (ADLPE). Probands and their sons had hyperinsulinemia resultant in more frequent AFLPE while in probands' wives and daughters higher IRI levels brought about opposite results.
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