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  • Title: [Transfer of the genetic information of oncornaviruses by means of tumor cell DNA].
    Author: Kniazev PG, Kuznetsov OK, Perevozchikov AP, Korobitsyn LP, Zhudina AI.
    Journal: Vopr Onkol; 1976; 22(1):47-53. PubMed ID: 178103.
    Abstract:
    The infection process was reproduced in the culture of chick embryonal cells by means of: a) DNA isolated from chick Rous sarcoma (Carr-Zilber strain); b) DNA from blood cells of chicks with myeloblastosis (strain A); c) DNA from Rous virus malignified (Prague strain) rat cells (XC). Antigenic properties of the virus, transfected with DNA from chick Rous sarcoma, would differ from the original parental strain (Carr-Zilber RSV), that evidences the possibility of a partial transfer of genetic information in transfection. A suggestion is made on four presumable variants of oncornaviruses transfection by means of tumor cells DNA.
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