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  • Title: Decrease of frontal metabolism demonstrated by positron emission tomography in a population of healthy elderly volunteers.
    Author: Salmon E, Maquet P, Sadzot B, Degueldre C, Lemaire C, Franck G.
    Journal: Acta Neurol Belg; 1991; 91(5):288-95. PubMed ID: 1781265.
    Abstract:
    Frontal metabolism measured with positron emission tomography is shown to be decreased relatively to that in other cortical or sub-cortical areas, in a population of healthy elderly compared to young volunteers. Cortical atrophy or neuronal depopulation are unlikely to entirely explain this physiological phenomenon, and sub-cortico-cortical deactivation should play a role, analogous to that proposed in subcortical diseases.
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