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Title: Naamidines H and I, cytotoxic imidazole alkaloids from the Indonesian marine sponge Leucetta chagosensis. Author: Tsukamoto S, Kawabata T, Kato H, Ohta T, Rotinsulu H, Mangindaan RE, van Soest RW, Ukai K, Kobayashi H, Namikoshi M. Journal: J Nat Prod; 2007 Oct; 70(10):1658-60. PubMed ID: 17822294. Abstract: Two new imidazole alkaloids, naamidines H ( 1) and I ( 2), were isolated from the marine sponge Leucetta chagosensis, collected in North Sulawesi, Indonesia. The compounds ( 1 and 2) showed cytotoxicity against HeLa cells with IC50 values of 5.6 and 15 microg/mL, respectively.[Abstract] [Full Text] [Related] [New Search]