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  • Title: A case of Gorham's disease complicated by bilateral chylothorax.
    Author: Boyle MJ, Alison P, Taylor G, Lightbourne BA.
    Journal: Heart Lung Circ; 2008 Feb; 17(1):64-6. PubMed ID: 17822955.
    Abstract:
    Gorham's disease is a very rare disorder of uncertain aetiology, characterised by non-neoplastic proliferation of vascular or lymphatic channels within bone leading to resorption and replacement of osseous matrix with angiomatous tissue. Fewer than 200 cases have been reported in the literature. The complication of chylothorax is associated with a high morbidity and mortality. We present the case of a 17-year-old male with Gorham's disease of the sternum, clavicle and rib, complicated by bilateral chylothorax. Despite thoracic duct ligation and radiotherapy, the patient progressively deteriorated and died 36 weeks following initial presentation.
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