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  • Title: Genetics of psoriasis and psoriatic arthritis.
    Author: Mathieu A, Cauli A, Vacca A, Mameli A, Passiu G, Porru G, Piga M, Ibba V, Mura V, Sanna S.
    Journal: Reumatismo; 2007; 59 Suppl 1():25-7. PubMed ID: 17828355.
    Abstract:
    Psoriasis and psoriatic arthritis are linked diseases characterised by (distinct ?) immune-mediated pathogenetic mechanisms and by a genetic background interacting with environmental factors. Some candidate susceptibility genes have been studied extensively; they include HLA genes, genes within the HLA region and genes outside the HLA region; among them corneodesmosin and other genes of PSORS1 region, MICA and TNF-a polymorphisms. The main findings in the literature are discussed.
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