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  • Title: Bipolar disorder not otherwise specified: comparison with bipolar disorder I/II and major depression.
    Author: Joyce PR, Light KJ, Rowe SL, Kennedy MA.
    Journal: Aust N Z J Psychiatry; 2007 Oct; 41(10):843-9. PubMed ID: 17828658.
    Abstract:
    OBJECTIVE: To compare the personality, clinical and comorbidity characteristics of subjects meeting diagnostic criteria for bipolar disorder not otherwise specified (BDNOS) to those with major depression and bipolar I or II disorder. METHODS: A family-based study was undertaken on the molecular genetics of depression and personality, in which the proband had been treated for depression, regardless of history, of hypomania or mania. RESULTS: The 25 subjects with BDNOS were different to the 297 subjects with major depression and similar to 75 subjects with bipolar I or II disorder on social phobia, obsessive-compulsive disorder and substance dependence comorbidity. The BDNOS subjects also had personality traits more akin to the bipolar I or II disorder subjects, especially borderline personality traits and self transcendence. CONCLUSIONS: Subjects with BDNOS, based on a history of 1-3 day recurrent hypomanias, should be included within a broader bipolar spectrum.
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