These tools will no longer be maintained as of December 31, 2024. Archived website can be found here. PubMed4Hh GitHub repository can be found here. Contact NLM Customer Service if you have questions.
Pubmed for Handhelds
PUBMED FOR HANDHELDS
Search MEDLINE/PubMed
Title: Coverage and error models of protein-protein interaction data by directed graph analysis. Author: Chiang T, Scholtens D, Sarkar D, Gentleman R, Huber W. Journal: Genome Biol; 2007; 8(9):R186. PubMed ID: 17845715. Abstract: Using a directed graph model for bait to prey systems and a multinomial error model, we assessed the error statistics in all published large-scale datasets for Saccharomyces cerevisiae and characterized them by three traits: the set of tested interactions, artifacts that lead to false-positive or false-negative observations, and estimates of the stochastic error rates that affect the data. These traits provide a prerequisite for the estimation of the protein interactome and its modules.[Abstract] [Full Text] [Related] [New Search]