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  • Title: Renierosides, cerebrosides from a marine sponge Haliclona (Reniera) sp.
    Author: Mansoor TA, Shinde PB, Luo X, Hong J, Lee CO, Sim CJ, Son BW, Jung JH.
    Journal: J Nat Prod; 2007 Sep; 70(9):1481-6. PubMed ID: 17848089.
    Abstract:
    Guided by the brine shrimp lethality assay, eight new cerebrosides (1-8) have been isolated from an extract of the marine sponge Haliclona (Reniera) sp. A novel feature of these cerebrosides was the presence of unprecedented amide-linked long-chain fatty acid moieties. The planar structures of the cerebrosides (1-8) were established by 1D and 2D NMR spectroscopic techniques, mass spectrometric analyses, and chemical degradation methods. The isolated compounds did not display cytotoxicity to a panel of five human solid tumor cell lines.
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