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  • Title: Non-transferrin-bound iron in plasma following administration of oral iron drugs.
    Author: Dresow B, Petersen D, Fischer R, Nielsen P.
    Journal: Biometals; 2008 Jun; 21(3):273-6. PubMed ID: 17851733.
    Abstract:
    Non-transferrin-bound iron (NTBI) was detected in serum samples from volunteers with normal iron stores or from patients with iron deficiency anaemia after oral application of pharmaceutical iron preparations. Following a 100 mg ferrous iron dosage, NTBI values up to 9 muM were found within the time period of 1-4 h after administration whereas transferrin saturation was clearly below 100%. Smaller iron dosages (10 and 30 mg) gave lower but still measurable NTBI values. The physiological relevance of this finding for patients under iron medication has to be elucidated.
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