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  • Title: [The origin of hyperprolactinemia associated with infertility and its treatment with Bromocriptin-Richter tablets].
    Author: Farkas M, Tárczy C, Tóth E.
    Journal: Acta Pharm Hung; 1991 Sep; 61(5):262-76. PubMed ID: 1785356.
    Abstract:
    Authors used the tablet Bromocriptine in 22 cases for the treatment of infertility and in 15 cases for that of extra-puerperal galactorrhoea. The serum-prolactin level of the patients of the two groups remained in 16 cases below and in 13 cases beyond of the upper value of the normal menstrual cycle. It turned out, that the average prolactin-level of patients, treated against infertility, diminished significantly even after one month after the treatment. Between the values of serum FSH, before and after LH treatment there have not been found any significant difference. On the contrary, in the values of serum progesterone and 17-beta-oestradiol significant differences have been observed after treatments of one month as well as of two months duration. On the basis of the results, authors can state, that the prevailing progesterone-level is the adequate indicator of potential fertility. During the treatment of hyperprolactinaemic pathologies eight pregnancies occurred (21.6%). It turned out, that hyperprolactinaemia was the real cause of procured abortion. For the registration of latent hyperprolactinaemia the Cerucal (metoclopramide) load proved to be an adequate diagnostical method.
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