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Title: Brunneins A-C, beta-carboline alkaloids from Cortinarius brunneus. Author: Teichert A, Schmidt J, Porzel A, Arnold N, Wessjohann L. Journal: J Nat Prod; 2007 Sep; 70(9):1529-31. PubMed ID: 17854153. Abstract: Four beta-carboline alkaloids, brunneins A-C (1-3) and 3-(7-hydroxy-9H-beta-carboline-1-yl)propanoic acid (4), were isolated from fruiting bodies of the agaricoid fungus Cortinarius brunneus. The structures of 1-3 were determined by analysis of NMR and MS data, and the structure of compound 4 was determined by comparison with published data. Brunnein A (1) exhibited very low cholinesterase inhibitory effects and no cytotoxicity.[Abstract] [Full Text] [Related] [New Search]