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  • Title: t(5;12)(q13;p13) in acute myeloid leukemia with preceding granulocytic sarcoma.
    Author: Park TS, Song J, Lee KA, Lee SG, Min YH, Choi JR.
    Journal: Cancer Genet Cytogenet; 2007 Sep; 177(2):158-60. PubMed ID: 17854675.
    Abstract:
    A 56-year-old woman was brought to the emergency room with gum swelling and pain. Biopsy of the gingiva revealed sheet-like proliferation of myeloperoxidase and CD45-positive large cells, and she was diagnosed with granulocytic sarcoma. Two years later, bone marrow involvement of granulocytic sarcoma was suspected. Her chromosome study repeatedly revealed a 46,XX,t(5;12)(q13;p13) karyotype. Case reports of t(5;12)(q13;p13) are extremely rare in the literature. To our knowledge, this is the first report of t(5;12)(q13;p13) in a patient with acute myelogenous leukemia with preceding granulocytic sarcoma.
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