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  • Title: [Lithium carbonate augmentation in tricyclic antidepressant-resistant depression].
    Author: Dorevitch A, Ginath Y.
    Journal: Harefuah; 1991 Dec 01; 121(11):429-30. PubMed ID: 1786889.
    Abstract:
    Combinations of lithium carbonate and tricyclic antidepressants are effective in the treatment of resistant unipolar depression. We present a case in which addition of lithium carbonate to a maximal dose of desipramine provided rapid and sustained improvement in a severely depressed 57-year-old woman. She had previously failed to respond to maximum doses of antidepressant drugs of 2 different classes. Although the lithium-tricyclic combination was successful in our case, we caution against its routine use.
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