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  • Title: Dexmedetomidine as sole sedative for awake intubation in management of the critical airway.
    Author: Abdelmalak B, Makary L, Hoban J, Doyle DJ.
    Journal: J Clin Anesth; 2007 Aug; 19(5):370-3. PubMed ID: 17869990.
    Abstract:
    We report a series of successful awake fiberoptic intubations in patients with critical (unstable, difficult) airways using the alpha(2)-agonist, dexmedetomidine. Dexmedetomidine has several desirable pharmacologic properties, including sedation, anxiolysis, hypnosis, analgesia, amnesia, antisialagogue effects, and a unique respiratory-sparing effect. Dexmedetomidine appears to be a useful agent for sedation during awake fiberoptic intubation in difficult airway patients.
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