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  • Title: Synthesis of novel functionalized 3-spiropyrrolizidine and 3-spiropyrrolidine oxindoles from Baylis-Hillman adducts of isatin and heteroaldehydes with azomethine ylides via [3+2]-cycloaddition.
    Author: Shanmugam P, Viswambharan B, Madhavan S.
    Journal: Org Lett; 2007 Oct 11; 9(21):4095-8. PubMed ID: 17877359.
    Abstract:
    A novel regioselective synthesis of a number of functionalized 3-spiropyrrolizidine and 3-spiropyrrolidine oxindoles from Baylis-Hillman adducts of isatin and heteroaldehydes via [3+2] cycloaddition of azomethine ylides in excellent yields has been reported.
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