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  • Title: Nephrotic syndrome resulting from focal segmental glomerulosclerosis in a peripheral blood stem cell transplant patient.
    Author: Heras M, Saiz A, Sánchez R, Fernandez-Reyes MJ, Mampaso F, Queizán J, Molina A, Vázquez L, Alvarez-Ude F.
    Journal: J Nephrol; 2007; 20(4):495-8. PubMed ID: 17879218.
    Abstract:
    We describe the case of a male patient who was diagnosed with acute monoblastic leukemia and received a peripheral stem cell transplantation (PSCT) with peripheral blood hematopoietic progenitors. Because he was in clinical remission with no evidence of chronic graft-versus-host disease (GVHD), immunosuppression was withdrawn, and he developed nephrotic syndrome (NS) months later. A kidney biopsy showed focal segmental glomerulosclerosis (FSGS) as part of the GVHD. Soon after the reintroduction of previous immunosuppressive therapy, we observed a complete remission of the NS.
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