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  • Title: Dried blood spots versus sera for detection of rubella virus-specific immunoglobulin M (IgM) and IgG in samples collected during a rubella outbreak in Peru.
    Author: Helfand RF, Cabezas C, Abernathy E, Castillo-Solorzano C, Ortiz AC, Sun H, Osores F, Oliveira L, Whittembury A, Charles M, Andrus J, Icenogle J.
    Journal: Clin Vaccine Immunol; 2007 Nov; 14(11):1522-5. PubMed ID: 17881506.
    Abstract:
    Most persons with rubella virus-specific immunoglobulin M (IgM)- or IgG-positive sera tested positive (98% [n = 178] and 99% [n = 221], respectively) using paired filter paper dried blood spot (DBS) samples, provided that DBS indeterminate results were called positive. For persons with IgM- or IgG-negative sera, 97% and 98%, respectively, were negative using DBS.
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