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  • Title: Characterization of CTX-M-22 and TEM-141 Encoded by a single plasmid from a clinical isolate of Enterobacter cloacae in China.
    Author: Liu G, Ling BD, Xie YE, Lin L, Zeng Y, Zhang X, Lei J.
    Journal: Jpn J Infect Dis; 2007 Sep; 60(5):295-7. PubMed ID: 17881870.
    Abstract:
    We analyzed the resistance to expanded-spectrum cephalosporins of an Enterobacter cloacae clinical isolate, EC002, by transconjugation, isoelectric-focusing analysis, and cloning experiments. It produced two beta-lactamases with isoelectric point values of 5.4 and 8.7, corresponding to TEM-141, a novel variant of TEM-1, and CTX-M-22, encoded by a transferable plasmid.
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