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  • Title: Dark-blood MRI of the thoracic aorta with 3D diffusion-prepared steady-state free precession: initial clinical evaluation.
    Author: Koktzoglou I, Kirpalani A, Carroll TJ, Li D, Carr JC.
    Journal: AJR Am J Roentgenol; 2007 Oct; 189(4):966-72. PubMed ID: 17885072.
    Abstract:
    OBJECTIVE: The purpose of this study was to compare the performance of 3D diffusion-prepared balanced steady-state free precession (SSFP) imaging with that of 3D contrast-enhanced MR angiography in evaluation of the thoracic aorta. MATERIALS AND METHODS: Twenty-one patients with indications for contrast-enhanced MR angiography and diffusion-prepared SSFP of the thoracic aorta were involved in this retrospective chart review study conducted with 1.5-T MRI. Two observers scored the quality of the contrast-enhanced MR angiographic and diffusion-prepared SSFP images on the basis of depicting the thoracic aorta. Image quality scores and diametric measurements of the aorta from both image sets were compared. RESULTS: Diametric measurements of the thoracic aorta showed a strong linear association (r = 0.971, p < 0.0001; regression line indifferent from line of equality, p < 0.05). The aortic root was better visualized with contrast-enhanced MR angiography (image quality score, 3.6 +/- 0.9 vs 3.0 +/- 0.8 of 5; p < 0.05); however, the aortic wall was better visualized with diffusion-prepared SSFP (image quality score, 4.4 +/- 0.6 vs 1.9 +/- 0.3 of 5; p < 0.0001). CONCLUSION: Three-dimensional diffusion-prepared SSFP yields better image quality than 3D contrast-enhanced MR angiography in evaluation of the thoracic aortic wall and appears to be a useful adjunct to 3D contrast-enhanced MR angiography for assessing aortic abnormalities before administration of a contrast agent.
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