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  • Title: F-18 FDG PET/CT staging of multiple myeloma with diffuse osseous and extramedullary lesions.
    Author: Wiesenthal AA, Nguyen BD.
    Journal: Clin Nucl Med; 2007 Oct; 32(10):797-801. PubMed ID: 17885362.
    Abstract:
    Multiple myeloma is the most common plasma cell neoplasm, with abnormal clonal proliferation of B cells in bone marrow. Its staging is important for therapeutic management and prognosis. F-18 FDG PET/CT is of proven value in staging and posttherapeutic monitoring multiple myeloma. Through imaging integration, PET provides functional detection of high metabolic lesions whereas CT provides correlated anatomic localization. The authors present a case of multiple myeloma status post chemotherapy and stem cell transplant with diffuse osseous and extramedullary lesions evaluated by PET/CT. The extramedullary involvement concerns the maxillary sinus, thyroid cartilage, mediastinum, retroperitoneum, neuroforamen, and epidura.
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