These tools will no longer be maintained as of December 31, 2024. Archived website can be found here. PubMed4Hh GitHub repository can be found here. Contact NLM Customer Service if you have questions.


Pubmed for Handhelds

PUBMED FOR HANDHELDS

Search MEDLINE/PubMed

  • Title: Trypanocidal tetrahydrofuran lignans from Peperomia blanda.
    Author: Felippe LG, Baldoqui DC, Kato MJ, Bolzani Vda S, Guimarães EF, Cicarelli RM, Furlan M.
    Journal: Phytochemistry; 2008 Jan; 69(2):445-50. PubMed ID: 17888465.
    Abstract:
    Five tetrahydrofuran lignans and two known flavones were isolated from the aerial parts of Peperomia blanda. The structures of the isolated lignans were elucidated by interpretation of their spectroscopic data, including by gHMQC and gHMBC. The relative and absolute configurations of the isolates were determined from NOESY interactions and optical properties, respectively. Four of the lignans were diastereomeric whilst one was of mixed biosynthetic origin. All but one of the lignans exhibited high in vitro trypanocidal activity when assayed against epimastigotes of Trypanosoma cruzi strain Y.
    [Abstract] [Full Text] [Related] [New Search]