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  • Title: Supernumerary ring chromosomes accompanied with near-tetraploidy following chemotherapy and cranial radiation in a girl with a relapsed acute lymphoblastic leukemia.
    Author: Gindina T, Kondakova E, Mamaev N.
    Journal: Cancer Genet Cytogenet; 2007 Oct 01; 178(1):82-4. PubMed ID: 17889715.
    Abstract:
    Supernumerary ring chromosomes of different sizes and near-tetraploidy were presented in the bone marrow cells of 12-year-old girl with relapsed acute lymphoblastic leukemia who had been treated previously with chemotherapy and cranial radiation. Despite significant chromosomal abnormalities, complete hematologic and cytogenetic remissions were achieved.
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