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  • Title: Comparison of automated assays for the determination of vitamin B12 in serum.
    Author: Vogeser M, Lorenzl S.
    Journal: Clin Biochem; 2007 Nov; 40(16-17):1342-5. PubMed ID: 17889846.
    Abstract:
    OBJECTIVES: To study the agreement of serum cobalamin results obtained with three different widely used analyzers. DESIGN AND METHODS: Comparative measurement of 100 serum samples was performed using the Abbott Architect, the Bayer Centaur, and the Roche Elecsys 2010 analyzer. RESULTS: Relatively close numeric correlation of the results was found with Pearson's r>0.95 for all three comparisons; however, the mean concentration of the highest reading and the lowest reading method differed by 16%. CONCLUSIONS: Relatively good agreement of results from three automated serum cobalamin assays was observed.
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