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  • Title: Prevalence of hysteroscopic findings and histologic diagnoses in patients with abnormal uterine bleeding.
    Author: Lasmar RB, Dias R, Barrozo PR, Oliveira MA, Coutinho Eda S, da Rosa DB.
    Journal: Fertil Steril; 2008 Jun; 89(6):1803-7. PubMed ID: 17889860.
    Abstract:
    OBJECTIVE: To describe the prevalence of hysteroscopic findings and histologic diagnoses in patients with abnormal uterine bleeding (AUB). DESIGN: Retrospective series of consecutive patients. SETTING: Tertiary care university hospital and private office. PATIENT(S): Four thousand fifty-four hysteroscopies with biopsy in patients with AUB evaluated between June 1993 and December 2004. INTERVENTION(S): Hysteroscopies were performed using 2.9-mm or 4-mm telescopes with CO(2) or saline as the distension media. Biopsies were done with a 5-mm grasper or with a Novak's curette. MAIN OUTCOME MEASURE(S): Prevalence of hysteroscopic findings and histologic analysis of biopsies. RESULT(S): Endometrial polyp was the most frequent hysteroscopic finding, accounting for 1,374 (33.9%) cases. Normal uterine cavity and cervical canal were found in 814 (20.1%) patients. Submucous fibroids were diagnosed in 302 (7.5%) women. Normal endometrium was the most frequent histologic diagnosis, accounting for 1,888 (46.6%) cases. Endometrial polyp was found in 1,115 (27.5%) patients. Endometrial hyperplasia was diagnosed in 613 (15.1%) and endometrial cancer in 105 (2.6%) women. CONCLUSION(S): Endometrial polyps are the most frequent hysteroscopic findings in patients with AUB, whereas normal endometrium is the most frequent histologic diagnosis.
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