These tools will no longer be maintained as of December 31, 2024. Archived website can be found here. PubMed4Hh GitHub repository can be found here. Contact NLM Customer Service if you have questions.


Pubmed for Handhelds

PUBMED FOR HANDHELDS

Search MEDLINE/PubMed

  • Title: Discovery of 5-HT6 receptor ligands based on virtual HTS.
    Author: Tasler S, Kraus J, Wuzik A, Müller O, Aschenbrenner A, Cubero E, Pascual R, Quintana-Ruiz JR, Dordal A, Mercè R, Codony X.
    Journal: Bioorg Med Chem Lett; 2007 Nov 15; 17(22):6224-9. PubMed ID: 17892934.
    Abstract:
    Based on a pharmacophore alignment on a 5-HT(6) ligand applying 4SCan technology, a new lead series was identified and further structurally investigated. K(i)s down to 8 nM were achieved.
    [Abstract] [Full Text] [Related] [New Search]