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  • Title: Intracranial time-of-flight MR angiography at 7T with comparison to 3T.
    Author: von Morze C, Xu D, Purcell DD, Hess CP, Mukherjee P, Saloner D, Kelley DA, Vigneron DB.
    Journal: J Magn Reson Imaging; 2007 Oct; 26(4):900-4. PubMed ID: 17896360.
    Abstract:
    PURPOSE: To establish the feasibility of intracranial time-of-flight (TOF) MR angiography (MRA) at 7T using phased array coils and to compare its performance to 3T. MATERIALS AND METHODS: In an initial study, five normal volunteers were scanned at 7T and 3T using eight-channel coils and standard acquisition parameters from a clinical TOF protocol. In a second study three additional studies were performed at 7T and 3T using empirically optimized 7T parameters. Contrast-to-noise (CNR) values were measured for major vessel segments. RESULTS: All measurements documented CNR increases at 7T, with a mean increase of 83% in the initial study and 88% in the second study. The CNR values achieved using the latter protocol were similar to the values obtained in the initial study, despite the 42% reduction expected due to the higher spatial resolution. CNR in the smaller peripheral vessels was increased dramatically, resulting in excellent visualization at high resolution. CONCLUSION: TOF MRA at 7T demonstrated improved visualization of the intracranial vasculature, particularly the smaller peripheral vessels, and may benefit studies of small aneurysms, atherosclerosis, vasospasm, and vasculitis.
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