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  • Title: [Preoperative treatments of rectal cancers].
    Author: Bosset JF, Nguyen F, Bosset M, Servagi-Vernat S, Sedrati A, Lorgis V.
    Journal: Cancer Radiother; 2007 Nov; 11(6-7):349-52. PubMed ID: 17897858.
    Abstract:
    Surgery alone is no longer appropriate to the treatment of T3-T4 resecable rectal cancer. Preoperative chemoradiotherapy has recently been approved as the new standard treatment. This approach improves local control with local failure rate raranging now around 6-8%. However, it does not impact on overall survival. It becomes urgent to develop new concepts and a basic research in the understanding of the biological mechanisms that may explain the resistance of the micrometastatic process.
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