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  • Title: Evaluation of partial carbon dioxide rebreathing cardiac output measurement during thoracic surgery.
    Author: Ng JM, Chow MY, Ip-Yam PC, Goh MH, Agasthian T.
    Journal: J Cardiothorac Vasc Anesth; 2007 Oct; 21(5):655-8. PubMed ID: 17905269.
    Abstract:
    OBJECTIVE: Noninvasive partial CO2 rebreathing (NICO; Novametrix Medical Systems, Inc, Wallingford, CT) is a relatively new alternative to thermodilution (TDCO) for measurement of cardiac output. This study compares the 2 methods during thoracic surgery and one-lung ventilation. DESIGN: A prospective, observational study. SETTING: A tertiary hospital. PARTICIPANTS: Twelve adult patients undergoing elective thoracotomy and one-lung ventilation in the lateral decubitus position. INTERVENTIONS: Paired measurements of cardiac output were performed during (1) 2-lung ventilation in the supine position (postinduction of anesthesia), (2) 10 minutes after initiation of one-lung ventilation in the lateral decubitus position with the nondependent chest open, and (3) after 30 minutes on one-lung ventilation. An average of 3 consecutive (10 mL 20 degrees C saline) TDCO measurements made during end-expiration was compared with corresponding NICO measurements. MEASUREMENTS AND MAIN RESULTS: The NICO showed a tendency to underestimate cardiac output compared with TDCO at all measurement times. Overall, bias was -0.29 L/min and limits of agreement -1.69 to 1.43 L/min. CONCLUSIONS: There was a moderate agreement between cardiac output measurements obtained with the NICO and TDCO. The present data suggest that the NICO technique may be useful during thoracic surgery.
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