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  • Title: Hepatitis A super infection as a cause of liver failure in a child with Wilson's disease.
    Author: Ozçay F, Canan O, Akcan B, Bilezikçi B.
    Journal: Turk J Pediatr; 2007; 49(2):199-202. PubMed ID: 17907522.
    Abstract:
    Infection with hepatitis A virus can cause severe or even fatal illness in patients with chronic liver disease. Here we describe a seven-year-old girl who presented as acute liver failure and was diagnosed with Wilson's disease and later with coexistent hepatitis A infection. Wilson's disease was demonstrated on the basis of low ceruloplasmin, high urinary copper excretion, histological evidence of cirrhosis, and high biochemical estimation of liver copper concentration. Hepatitis A was diagnosed serologically. Our case suggests that acute hepatitis A may play a part in the acute decompensation seen in some cases of unrecognized Wilson's disease. We also emphasize the importance of prevention measures of hepatitis A infection in patients with chronic liver disease.
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