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  • Title: [Early pleuropulmonary toxicity associated with cabergoline, an antiparkinsonian drug].
    Author: Villavicencio C, Ramírez-Sarmiento A, Gayete A, Grau S, Orozco-Levi M.
    Journal: Arch Bronconeumol; 2007 Sep; 43(9):519-22. PubMed ID: 17919420.
    Abstract:
    We report a case of pleural effusion, pericardial thickening, and pulmonary involvement in a patient with dry cough, dyspnea, edema, and changes in the skin of the lower limbs. Treatment with cabergoline (Sogilen) had been started 4 months earlier. Pleural effusion, pericardial thickening, and impaired pulmonary function (airflow obstruction, increased airway resistance, and reduced carbon monoxide diffusing capacity) were observed. The Naranjo scale pointed to a probable relationship between cabergoline and these adverse effects. We report on outcome after 2 months of follow-up, during which time there was a slow and incomplete improvement in respiratory function. This is the first case in our practice setting of early pleuropulmonary toxicity associated with cabergoline.
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