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  • Title: Screening of terpenes and derivatives for antimycobacterial activity; identification of geranylgeraniol and geranylgeranyl acetate as potent inhibitors of Mycobacterium tuberculosis in vitro.
    Author: Vik A, James A, Gundersen LL.
    Journal: Planta Med; 2007 Oct; 73(13):1410-2. PubMed ID: 17924309.
    Abstract:
    Several terpenes as well as synthetic analogues were screened for activity against Mycobacterium tuberculosis in vitro using the microplate alamar blue assay . Geranylgeraniol (MIC 1.56 microg/mL) and geranylgeranyl acetate (MIC 3.13 microg/mL) were identified as potent and selective inhibitors of M. tuberculosis.
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