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  • Title: A new asymmetric synthesis of the anti-tumor alkaloid (R)-(+)-crispine A.
    Author: Allin SM, Gaskell SN, Towler JM, Page PC, Saha B, McKenzie MJ, Martin WP.
    Journal: J Org Chem; 2007 Nov 09; 72(23):8972-5. PubMed ID: 17924694.
    Abstract:
    We report a novel, facile, and asymmetric approach for the synthesis of the anti-tumor alkaloid (+)-crispine A via a highly diastereoselective N-acyliminium cyclization reaction as a key synthetic step.
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