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  • Title: [Clinical trials in dermatology. Evaluation of the tolerability and efficacy of a topical antifungal agent in the treatment of superficial mycoses].
    Author: Queille-Roussel C, Dahan C, Duteil L, Schaefer H, Revuz J, De Prost Y, Guillaume JC, Ortonne JP, Czernielewski J.
    Journal: Therapie; 1991; 46(3):201-4. PubMed ID: 1792652.
    Abstract:
    There is no single method for evaluating topical antifungal drugs. The localisation and the type of fungal, determine the treatment duration (from few days to several months). The main methodological characteristics of clinical trials in tinea pedis treatment (athlete's foot type) are reported. Aspects related to other clinical forms such as tinea versicolor and onychomycosis are also described. In any case, the main criteria of activity remains the mycological examination based on KOH microbiology and culture performed at the end of the treatment and again afterwards.
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