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Title: Infliximab: new indication. Ulcerative colitis: caution is needed due to long-term risks. Journal: Prescrire Int; 2007 Oct; 16(91):194. PubMed ID: 17926832. Abstract: When treatment for ulcerative colitis with steroids and immunosuppressants is ineffective or poorly tolerated, two placebo-controlled trials have demonstrated that infliximab yields remissions permitting steroid withdrawal in about 20% of patients. However, the long-term risks of infections and cancer mean that infliximab should be reserved for the most severely ill patients.[Abstract] [Full Text] [Related] [New Search]