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Title: Evaluation of O-POSSUM in predicting in-hospital mortality after resection for oesophageal cancer. Author: Lagarde SM, Maris AK, de Castro SM, Busch OR, Obertop H, van Lanschot JJ. Journal: Br J Surg; 2007 Dec; 94(12):1521-6. PubMed ID: 17929231. Abstract: BACKGROUND: The aims of the present study were to validate the Physiological and Operative Severity Score for the enUmeration of Mortality adjusted for oesophagogastric surgery (O-POSSUM). METHODS: Data on patients who underwent potentially curative oesophagectomy in a tertiary referral centre for adenocarcinoma or squamous cell carcinoma of the oesophagus were analysed. The in-hospital mortality predicted by O-POSSUM was compared with the actual value by linear analysis. RESULTS: Twenty-four (3.6 per cent) of 663 patients died in hospital. The observed : predicted ratio for in-hospital mortality was 0.29. The model had a poor fit (P < 0.001). The area under the receiver-operator characteristic curve was 0.60 (95 per cent confidence interval 0.47 to 0.72); P = 0.113). O-POSSUM score was not related to the severity of complications. CONCLUSION: O-POSSUM overpredicted in-hospital mortality threefold and could not identify patients at higher risk of death. O-POSSUM needs substantial modification before it can be used for comparison of treatment outcomes between centres.[Abstract] [Full Text] [Related] [New Search]